Species:Mouse MonoclonalClone:4C7Isotype:IgG2aMW:100 kDSpecies Reactivity:Human.Not reactive with mouse or rat.Specificity:The basement membrane (BM) is a component of the extracellular matrix and is composed of a variety of proteins, of which laminin is the most prevalent. Laminin is synthesized by fibroblasts in epithelial and endothelial cells, as well as smooth muscle cells. This protein normally contributes to the regulation of cell growth, cell attachment to the BM and to the morphology of cells and their urigation.The monoclonal labels trophoblastic cells of the villous trophoblastic epithelium in the placenta, and epithelia and BM in normal tonsil. Extensive studies of a variety of invasive and non-invasive carcinomas, including their benign counterparts, demonstrated a lack of immunoreactivity for laminin in the majority of invasive carcinomas. Benign or non-invasive lesions showed intact BM.

ScyTek始建于1991年，以成为世界级生命科学研究试剂生产商为目标。ScyTek从创立之初开始, 就采取了严格的原材料筛选程序，确保所有出厂产品都具有最高的品质

按照为工业客户提供OEM服务以及同时服务科研市场的策略，ScyTek能够进行大批量生产而保持总成本降到最低，始终坚持为客户传递其成本优势的政策。

如今， ScyTek生产多种优质试剂，不断应用于各种学科，包括免疫学，组织学，细胞学，微生物学和血液学等.